Because transpulmonary pressure in ARDS patient might be of great interest for alveolar recruitment or the risk of VILI, we had end inspiratory relative transpulmonary pressure in the ARDS model. We compared SimVA modelisation to the study from Grasso et al. in H1N1 ARDS patients proposed for ECMO treatment.
This screen copy of SimVA illustrates end inspiratory relative transpulmonary pressure (PL,ER) with a PEEP of 17 cmH20 and a VT of 5.1 ml/kg PBW, plateau pressure of 31 cmH2O and thoracopulmonar of 27 ml/cmH2O, the resulting PL,ER is 18 with a Chest Wall elastance of 17 cmH20/ml.
This screen copy of SimVA illustrates the increase of PEEP to 21 in order to have a PL,ER close to 25 cmH2O, with a VT of 5.1 ml/kg PBW, plateau pressure of 38 cmH2O and thoracopulmonar of 23 ml/cmH2O, with the same Chest Wall elastance.